Article
Association between polymorphisms in the vitamin D receptor and susceptibility to multiple sclerosis.
Pharmacogenetics and genomics - 1 Feb 2021
Cancela Díez Bárbara, Pérez-Ramírez Cristina, Maldonado-Montoro María Del Mar, Carrasco-Campos María Isabel, Sánchez Martín Almudena, Pineda Lancheros Laura Elena, Martínez-Martínez Fernando, Calleja-Hernández Miguel Ángel, Ramírez-Tortosa María Carmen, Jiménez-Morales Alberto
Abstract excerpt
OBJECTIVES: Multiple sclerosis (MS) is a neurodegenerative chronic inflammatory. Mutations in the vitamin D receptor (VDR) gene can substantially affect serum vitamin D levels or alter its functionality, and can consequently increase susceptibility to developing MS. The objective of this study was to evaluate the association between polymorphisms in the VDR gene and risk of MS in a (Spanish) Caucasian population....
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