Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis.

doi:10.1016/j.jneuroim.2008.12.011

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Article

Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis.

Journal of neuroimmunology - 15 Feb 2009

Smolders Joost, Damoiseaux Jan, Menheere Paul, Tervaert Jan Willem Cohen, Hupperts Raymond

Abstract excerpt

Multiple sclerosis (MS) has been associated with low levels of 25-hydroxyvitamin D (25(OH)D). Several genetic polymorphisms of the vitamin D receptor gene (VDRG), of whom Fok-I (rs10735810) has functional consequences for receptor protein structure and the immune system, have been studied in relation to MS with variable results. The purpose of our study was to assess an association of the Fok-I VDRG polymorphism...

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PMID: 19178954
DOI: 10.1016/j.jneuroim.2008.12.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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