Article
Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis.
Neurology - 19 Aug 2008
Dwyer T, van der Mei I, Ponsonby A-L, Taylor B V, Stankovich J, McKay J D, Thomson R J, Polanowski A M, Dickinson J L
Abstract excerpt
OBJECTIVE: Low past sun exposure, fair skin type, and polymorphisms of the MC1R gene have been associated with multiple sclerosis (MS) risk. We aimed to investigate the interplay between melanocortin 1 receptor gene variants, red hair/fair skin phenotype, and past environmental sun exposure in MS. METHODS: Population-based case-control study in Tasmania, Australia, involving 136 cases with MS and 272 controls...
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