Article
M. avium binding to HLA-DR expressed alleles in silico: a model of phenotypic susceptibility to sarcoidosis.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG - 1 Dec 2008
Saltini C, Pallante M, Puxeddu E, Contini S, Voorter C E, Drent M, Amicosante M
Abstract excerpt
Sarcoidosis is a systemic granulomatosis disease of unknown origin where a number of microbes, in particular M. tuberculosis and non-tuberculous mycobacteria, have been hypothesized to play a role in disease pathogenesis, possibly through bacterial antigen-driven hypersensitivity. To test this concept, we used bioinformatic tools allowing the identification of antigenic peptides in whole microbial genomes to...
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