Article
HLA class II amino acid epitopes as susceptibility markers of sarcoidosis.
Tissue antigens - 1 Jul 2007
Voorter C E M, Amicosante M, Berretta F, Groeneveld L, Drent M, van den Berg-Loonen E M
Abstract excerpt
Sarcoidosis is a multisystemic disorder of unknown etiology, affecting primarily the lung and characterized by epithelioid granulomas. Disease association studies showed human leukocyte antigen (HLA) class II to be related to sarcoidosis. Initially, we studied the association of sarcoidosis with DQB1, and in the present study, we evaluated all amino acid variants of the HLA-DPB1, -DQB1, -DRB1, -DRB3, -DRB4 and...
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