Article
Mycobacterial ESAT-6 and katG are recognized by sarcoidosis CD4+ T cells when presented by the American sarcoidosis susceptibility allele, DRB1*1101.
Journal of clinical immunology - 1 Jan 2010
Oswald-Richter Kyra, Sato Hiroe, Hajizadeh Rana, Shepherd Bryan E, Sidney John, Sette Alessandro, Newman Lee S, Drake Wonder Puryear
Abstract excerpt
INTRODUCTION: Genetic associations of American sarcoidosis susceptibility implicate MHC class II allele, DRB1*1101. We previously reported immune recognition of Mycobacterium peptides from peripheral cells of 26 sarcoidosis subjects, 24 PPD- healthy volunteers, and eight with latent tuberculosis...
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