Study designs in genetic epidemiology.

Abstract excerpt

Identification of germline mutations that may modulate individual risk of developing cancer is a rapidly developing field. Over the last few decades, germline mutations in p53, BRCA1, BRCA2, APC, MLH1, MSH2, and MSH6 have been identified in families with a large number of relatives who have been diagnosed with particular types of cancer. These mutations are rare but substantially increase the risk of cancer in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Epidemiologic Methods
• Share to APC gene
• Share to MLH1 gene