Genetic association studies.

doi:10.1016/S0140-6736(05)67424-7

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Article

Genetic association studies.

Lancet (London, England) - 1 Jan 2000

Cordell Heather J, Clayton David G

Abstract excerpt

We review the rationale behind and discuss methods of design and analysis of genetic association studies. There are similarities between genetic association studies and classic epidemiological studies of environmental risk factors but there are also issues that are specific to studies of genetic risk factors such as the use of particular family-based designs, the need to account for different underlying genetic...

Topics

Epistasis, Genetic
Gene Frequency
Genetic Linkage
Genetic Predisposition to Disease
Genetics, Population
Genotype
Humans
Linkage Disequilibrium
Phenotype
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 16182901
DOI: 10.1016/S0140-6736(05)67424-7

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