Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Function of retinoic acid receptors during embryonic development.

Nuclear receptor signaling - 1 Jan 2009

Mark Manuel, Ghyselinck Norbert B, Chambon Pierre

Abstract excerpt

Retinoids, the active metabolites of vitamin A, regulate complex gene networks involved in vertebrate morphogenesis, growth, cellular differentiation and homeostasis. Studies performed in vitro, using either acellular systems or transfected cells, have shown that retinoid actions are mediated through heterodimers between the RAR and RXR nuclear receptors. However, in vitro studies indicate what is possible, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic Development
Share to Mice
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Pregnancy

Share to Receptors, Retinoic Acid

Share to Retinoid X Receptors

Share to Retinoids in leukemia and cellular processes

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 19381305
DOI: 10.1621/nrs.07002
PMCID: PMC2670431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Function of retinoic acid receptors during embryonic development.PMID 19381305Read ↗

[Genetic control of the development by retinoic acid].Semantic proximity Read ↗

Developmental roles of the retinoic acid receptors.Semantic proximity Read ↗

Role of the retinoic acid receptor beta (RARbeta) during mouse developmentSemantic proximity Read ↗

Retinoid X receptors are essential for early mouse development and placentogenesis.Semantic proximity Read ↗

Embryonic development and pattern formationSemantic proximity Read ↗

Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid.Semantic proximity Read ↗

Chronicle of a discovery: the retinoic acid receptorSemantic proximity Read ↗

The molecular physiology of nuclear retinoic acid receptors. From health to diseaseSemantic proximity Read ↗

Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development.Semantic proximity Read ↗

Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.Semantic proximity Read ↗

Genetics and functions of the retinoic acid pathway, with special emphasis on the eye.Semantic proximity Read ↗

A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.