Developmental roles of the retinoic acid receptors.

doi:10.1016/0960-0760(95)00094-g

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Article

Developmental roles of the retinoic acid receptors.

The Journal of steroid biochemistry and molecular biology - 1 Jun 1995

Lohnes D, Mark M, Mendelsohn C, Dollé P, Decimo D, LeMeur M, Dierich A, Gorry P, Chambon P

Abstract excerpt

Retinoic acid, one of the principle active metabolites of vitamin A (retinol), is believed to be essential for numerous developmental and physiological processes. Vitamin A deprivation (VAD) during development leads to numerous congenital defects. Previous studies of retinoic acid receptor (RAR)...

Topics

Animals
Biological Evolution
Extremities
Female
Gene Expression Regulation, Developmental
Genes
Limb Deformities, Congenital
Male
Mice
Morphogenesis
Mutation
Neural Crest
Receptors, Retinoic Acid
Tretinoin

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