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Article

CYP17, GSTP1, PON1 and GLO1 gene polymorphisms as risk factors for breast cancer: an Italian case-control study.

BMC cancer - 20 Apr 2009

Antognelli Cinzia, Del Buono Chiara, Ludovini Vienna, Gori Stefania, Talesa Vincenzo N, Crinò Lucio, Barberini Francesco, Rulli Antonio

Abstract excerpt

BACKGROUND: Estrogens, environmental chemicals with carcinogenic potential, as well as oxidative and carbonyl stresses play a very important role in breast cancer (BC) genesis and progression. Therefore, polymorphisms of genes encoding enzymes involved in estrogen biosynthesis pathway and in the metabolic activation of pro-carcinogens to genotoxic intermediates, such as cytochrome P450C17alpha (CYP17), endogenous...

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Source

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Identifiers

PMID: 19379515
DOI: 10.1186/1471-2407-9-115
PMCID: PMC2680904

Genes

PON1
GLO1
GSTP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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