Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FGFR3 mutations in prostate cancer: association with low-grade tumors.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2009

Hernández Silvia, de Muga Silvia, Agell Laia, Juanpere Nuria, Esgueva Raquel, Lorente José A, Mojal Sergi, Serrano Sergio, Lloreta Josep

Abstract excerpt

Prostate cancer is the second cause of cancer-related death in men of the Western World. The role of FGFR3 and its abnormalities in prostate cancer are not known. FGFR3 mutations have been reported in some human tumors. Few studies have analyzed the mutations of FGFR3 in prostate tumors, and no mutations have been previously reported. Prevalence of FGFR3 somatic mutations was investigated in a series of prostate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colonic Neoplasms
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Neoplasms, Multiple Primary

Share to Prostatic Neoplasms

Share to Receptor, Fibroblast Growth Factor, Type 3

Share to Skin Neoplasms

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 19377444
DOI: 10.1038/modpathol.2009.46

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FGFR3 mutations in prostate cancer: association with low-grade tumors.PMID 19377444Read ↗

No evidence of FGFR3 mutations in prostate cancer.Semantic proximity Read ↗

Mutational activation of FGFR3 is not involved in the development of prostate cancer.Semantic proximity Read ↗

Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma.Semantic proximity Read ↗

Association of FGFR4 genetic polymorphisms with prostate cancer risk and prognosis.Semantic proximity Read ↗

KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer.Semantic proximity Read ↗

Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations.Semantic proximity Read ↗

FGFR3b Extracellular Loop Mutation Lacks Tumorigenicity In Vivo but Collaborates with p53/pRB Deficiency to Induce High-grade Papillary Urothelial Carcinoma.Semantic proximity Read ↗

FGFR3 mutational status and protein expression in patients with bladder cancer in a Jordanian population.Semantic proximity Read ↗

Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer.Semantic proximity Read ↗

[Correlation of FGFR3 mutations and chromosomal alterations in bladder cancer].Semantic proximity Read ↗

Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours.Semantic proximity Read ↗

Fibroblast growth factor receptor 3 gene (FGFR3) mutations in high-grade muscle-invasive urothelial bladder cancer in a Brazilian population: evaluation and prevalence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.