Article
FGFR3 mutational status and protein expression in patients with bladder cancer in a Jordanian population.
Cancer epidemiology - 1 Dec 2010
Bodoor Khaldon, Ghabkari Abdulhameed, Jaradat Ziad, Alkhateeb Asem, Jaradat Saied, Al-Ghazo Mohammed A, Matalka Ismail, Musleh Hisham, Haddad Yazan
Abstract excerpt
Bladder cancer accounts for nearly 5% of all newly diagnosed cancers in Jordan, with a much higher frequency in males. Recent studies have shown that activating mutations in FGFR3 are the most common findings in non-invasive low grade bladder tumors. In this study, we, retrospectively, investigated a cohort of 121 bladder cancer patients with various grades and stages of the tumor for molecular changes in FGFR3....
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