Article
Frequency of fibroblast growth factor receptor 3 mutations in sporadic tumours.
Oncogene - 19 Jul 2001
Sibley K, Stern P, Knowles M A
Abstract excerpt
Mutations in FGFR3 have been identified in several tumour types including bladder carcinoma, cervical carcinoma, and multiple myeloma. In bladder carcinoma, we recently identified FGFR3 mutations in 41% of tumours, making this the most frequently mutated putative oncogene identified in bladder cancer to date. We have now investigated the frequency of FGFR3 mutation in a panel of 125 tumours and 13 cell lines from...
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