Article
[Correlation of FGFR3 mutations and chromosomal alterations in bladder cancer].
Verhandlungen der Deutschen Gesellschaft fur Pathologie - 1 Jan 2006
Junker Kerstin, van Oers Johanna M M, Zwarthoff Ellen C, Kania Ines, Schubert Joerg, Hartmann Arndt
Abstract excerpt
It has been suggested that mutation of FGFR3 is associated with non-invasive tumors of low malignant potential and low risk of recurrence and progression. The aim of this study was to analyze the distribution of FGFR3 mutations in bladder tumors of different grade and stage and to determine the relation of FGFR3 mutations to chromosomal alterations detected by CGH. Frozen sections of 100 bladder cancer samples...
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