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Article

Fibroblast growth factor receptor 3 mutations in bladder tumors correlate with low frequency of chromosome alterations.

Neoplasia (New York, N.Y.) - 1 Jan 2008

Junker Kerstin, van Oers Johanna M M, Zwarthoff Ellen C, Kania Ines, Schubert Joerg, Hartmann Arndt

Abstract excerpt

The aim of this study was to analyze the distribution of FGFR3 mutations in bladder tumors of different grade and stage and determine the relation of mutations to chromosomal alterations detected by comparative genomic hybridization (CGH). One hundred bladder cancer samples served as templates for manual microdissection. DNA was isolated from dissected samples containing at least 80% tumor cells. Mutations in...

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Source

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Identifiers

PMID: 18231634
DOI: 10.1593/neo.07178
PMCID: PMC2213896

Genes

FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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