Article
Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans.
Neurobiology of disease - 1 Mar 2010
Molteni Raffaella, Cattaneo Annamaria, Calabrese Francesca, Macchi Flavia, Olivier Jocelien D A, Racagni Giorgio, Ellenbroek Bart A, Gennarelli Massimo, Riva Marco A
Abstract excerpt
In order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to depression under serotonin transporter (SERT) dysfunction, we analyzed the expression of brain-derived neurotrophic factor (BDNF), a key player in neuronal plasticity, which is implicated in the et...
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