Article
HBx protein modulates PI3K/Akt pathway to overcome genotoxic stress-induced destabilization of cyclin D1 and arrest of cell cycle.
Indian journal of biochemistry & biophysics - 1 Feb 2009
Mukherji A, Janbandhu V C, Kumar V
Abstract excerpt
Growth arrest represents an innate barrier to carcinogenesis. DNA damage and replicational stress are known to induce growth arrest and apoptotic death to avert genomic instability and consequently carcinogenesis. In this study, working on the genotoxic stress induced by hydroxyurea and methylmet...
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