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Cyclin degradation for cancer therapy and chemoprevention

14 Sept 2007

Abstract excerpt

Cancer is characterized by uncontrolled cell division resulting from multiple mutagenic events. Cancer chemoprevention strategies aim to inhibit or reverse these events using natural or synthetic pharmacologic agents. Ideally, this restores normal growth control mechanisms. Diverse classes of compounds have been identified with chemopreventive activity. What unites many of them is an ability to inhibit the cell...

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PMID: 17868090
DOI: 10.1002/jcb.21519

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