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Article

Contribution of genetic polymorphisms of stromal cell-derived factor-1 and its receptor, CXCR4, to the susceptibility and clinicopathologic development of oral cancer.

Head & neck - 1 Oct 2009

Teng Ying-Hock, Liu Te-Hsiung, Tseng Hsien-Chun, Chung Tsung-Te, Yeh Chia-Ming, Li Yu-Chiung, Ou Yu-Hsiang, Lin Long-Yau, Tsai Hsiu-Ting, Yang Shun-Fa

Abstract excerpt

BACKGROUND: The aim of this study was to evaluate the relations of SDF-1 and its receptor, CXCR4, gene variants on oral cancer risk. METHODS: PCR-RFLP was used to measure SDF-1-3'A and CXCR4 gene polymorphisms in 284 controls and 113 patients with oral cancer. RESULTS: After being adjusted for age, individuals with A/G heterozygotes of SDF-1 had a higher risk of 1.86-fold to develop oral cancer when compared with...

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Share to Carcinoma, Squamous Cell
Share to Chemokine CXCL12

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Agar Gel

Share to Gene Expression Regulation, Neoplastic

Share to Lymphatic Metastasis

Share to Mouth Neoplasms

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, CXCR4

Source

Identifiers

PMID: 19373784
DOI: 10.1002/hed.21094

Genes

CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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