Article
Effect of CC chemokine ligand 5 and CC chemokine receptor 5 genes polymorphisms on the risk and clinicopathological development of oral cancer.
Oral oncology - 1 Oct 2010
Weng Chia-Jui, Chien Ming-Hsien, Lin Chiao-Wen, Chung Tsung-Te, Zavras Athanasios-I, Tsai Chiung-Man, Chen Mu-Kuan, Yang Shun-Fa
Abstract excerpt
Inflammation can be induced by cytokines, chemokines, and their receptors, and it is believed to be a risk factor on tumor initiation and progression. The contribution of CC chemokine ligand 5 (CCL5) and CC chemokine receptor 5 (CCR5) on the risk and prognosis of oral cancer is still poorly investigated. The aims of this study were to investigate the impacts of single nucleotide polymorphisms (SNPs) in CCL5 and...
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