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Article

Impact of CCL4 gene polymorphisms and environmental factors on oral cancer development and clinical characteristics.

Oncotarget - 9 May 2017

Lien Ming-Yu, Lin Chiao-Wen, Tsai Hsiao-Chi, Chen Yng-Tay, Tsai Ming-Hsui, Hua Chun-Hung, Yang Shun-Fa, Tang Chih-Hsin

Abstract excerpt

In Taiwan, oral cancer has causally been associated with environmental carcinogens. CCL4 (C-C chemokine ligand 4), a macrophage inflammatory protein with a key role in inflammation and immune-regulation, was implicated in carcinogenesis by facilitating instability in the tumor environment. The purpose of this study was to identify gene polymorphisms of CCL4 specific to patients with oral squamous cell carcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mouth Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 28404909
DOI: 10.18632/oncotarget.15615
PMCID: PMC5458219

Genes

CCL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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