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Article

Mutational analysis of proto-oncogene Dbl on Xq27 in testicular germ cell tumors reveals a rare SNP in a patient with bilateral undescended testis.

World journal of urology - 1 Dec 2009

Xu Wan-Hai, Zhang Cheng, Zhao Wei-Ming, Li Chun-Mei, Xiu You-Cheng, Ni Shao-Bin, Ren Ming-Hua, Sun Dian-Jun

Abstract excerpt

OBJECTIVES: An abundance of X chromosomes in testicular germ cell tumors (TGCTs), and a candidate TGCTs susceptibility gene (TGCT1) on Xq27 highlight the potential involvement of X chromosomes in TGCT pathogenesis. However, the TGCT1 on Xq27 has so far not been identified. We hypothesized that a somatic mutation of dbl oncogene on Xq27 may play a role for the development of TGCTs. METHODS: We have screened 41...

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Share to Chromosomes, Human, X
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine Nucleotide Exchange Factors

Share to Neoplasms, Germ Cell and Embryonal

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins

Share to Testicular Neoplasms

Source

Identifiers

PMID: 19373475
DOI: 10.1007/s00345-009-0408-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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