Article
Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence.
Neoplasia (New York, N.Y.) - 1 Jan 2000
Skotheim R I, Kraggerud S M, Fosså S D, Stenwig A E, Gedde-Dahl T, Danielsen H E, Jakobsen K S, Lothe R A
Abstract excerpt
Testicular germ cell tumor (TGCT) is the most common tumor type among adolescent and young adult males. Familial clustering and bilateral disease are suggestive of a genetic predisposition among a subgroup of these patients, but susceptibility genes for testicular cancer have not yet been identified. However, suggestive linkage between disease and genetic markers has been reported at loci on chromosome arms 3q,...
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