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Article

Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour.

Journal of medical genetics - 1 Jul 2011

Kratz Christian P, Han Summer S, Rosenberg Philip S, Berndt Sonja I, Burdett Laurie, Yeager Meredith, Korde Larissa A, Mai Phuong L, Pfeiffer Ruth, Greene Mark H

Abstract excerpt

BACKGROUND: Familial testicular germ cell tumours (TGCTs) and bilateral TGCTs comprise 1-2% and 5% of all TGCTs, respectively, but their genetic basis remains largely unknown. AIM: To investigate the contribution of known testicular cancer risk variants in familial and bilateral TGCTs. METHODS AND RESULTS: The study genotyped 106 single nucleotide polymorphisms (SNPs) in four regions (BAK1, DMRT1, KITLG,...

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Share to bcl-2 Homologous Antagonist-Killer Protein
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

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Share to Neoplasms, Germ Cell and Embryonal

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Source

Open in PubMed Open full text

Identifiers

PMID: 21617256
DOI: 10.1136/jmedgenet-2011-100001
PMCID: PMC3131696

Genes

TERT
BAK1
DMRT1
KITLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variants in or near KITLG, BAK1, DMRT1, and TERT-CLPTM1L predispose to familial testicular germ cell tumour.PMID 21617256Read ↗

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