Article
Regulatory variation in hepcidin expression as a heritable quantitative trait.
Biochemical and biophysical research communications - 19 Jun 2009
Bayele Henry K, Srai Surjit K S
Abstract excerpt
Genetic variation underlies phenotypic diversity and complex quantitative traits including heritable diseases. We hypothesized that such variation may underlie or determine intrinsic inter-individual differences in iron metabolism and may also play a role in variable phenotypes associated with iron-related diseases. Using hepcidin as a marker of iron homeostasis, we assessed sequence variation and the...
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