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Article

Analysis of prepulse inhibition in mouse lines overexpressing 22q11.2 orthologues.

The international journal of neuropsychopharmacology - 1 Aug 2009

Stark Kimberly L, Burt Rachel A, Gogos Joseph A, Karayiorgou Maria

Abstract excerpt

Animal models have been useful in elucidating the genetic basis of the cognitive and behavioural phenotypes associated with the 22q11.2 microdeletions. Loss-of-function models have implicated a number of genes as playing a role in prepulse inhibition (PPI) of the startle response. Here, we report the generation and initial analysis of bacterial artificial chromosome (BAC) transgenic (Tg) mice, overexpressing...

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Source

Identifiers

PMID: 19519974
DOI: 10.1017/S1461145709000492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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