Article
Human Immunodeficiency Virus Integration Efficiency and Site Selection in Quiescent CD4 + T Cells
16 Apr 2009
Abstract excerpt
Until very recently, quiescent CD4(+) T cells were thought to be resistant to human immunodeficiency virus (HIV) infection. Subsequent studies, attempting to fully elucidate the mechanisms of resistance, showed that quiescent cells could become infected by HIV at low efficiency and form a latently infected population. In this study, we set out to identify the sites of viral integration and to assess the...
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