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A Sensitive, Quantitative Assay for Human Immunodeficiency Virus Type 1 Integration

4 Oct 2002

Abstract excerpt

Quantitative methods to measure human immunodeficiency virus type 1 (HIV-1) integration promise to be important tools in dissecting the mechanisms whereby latent reservoirs of provirus are established, most notably in the resting T cells of patients receiving antiretroviral therapy. Here we describe a fluorescence-monitored, nested PCR assay that is able to quantify the relatively rare integration events that...

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Identifiers

PMID: 12368337
DOI: 10.1128/jvi.76.21.10942-10950.2002

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