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Sites of retroviral DNA integration: From basic research to clinical applications

28 Oct 2015

Abstract excerpt

One of the most crucial steps in the life cycle of a retrovirus is the integration of the viral DNA (vDNA) copy of the RNA genome into the genome of an infected host cell. Integration provides for efficient viral gene expression as well as for the segregation of viral genomes to daughter cells upon cell division. Some integrated viruses are not well expressed, and cells latently infected with human...

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PMID: 26508664
DOI: 10.3109/10409238.2015.1102859

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