Article
Recurrent HIV‐1 Integration at theBACH2Locus in Resting CD4+T Cell Populations during Effective Highly Active Antiretroviral Therapy
2 Feb 2007
Abstract excerpt
The persistence of latent human immunodeficiency virus type 1 (HIV-1) has been considered one of the major obstacles for eradication of the virus in infected individuals receiving successful antiretroviral therapy. To determine the contribution of integration sites to viral latency within clinical settings, an inverse polymerase chain reaction method was used to analyze integration sites in CD4(+) T cells from...
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