Article
Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2009
Penney Kathryn L, Salinas Claudia A, Pomerantz Mark, Schumacher Fredrick R, Beckwith Christine A, Lee Gwo-Shu, Oh William K, Sartor Oliver, Ostrander Elaine A, Kurth Tobias, Ma Jing, Mucci Lorelei, Stanford Janet L, Kantoff Philip W, Hunter David J, Stampfer Meir J, Freedman Matthew L
Abstract excerpt
PURPOSE: Variants at chromosomal loci 8q24 and 17q are established risk factors for prostate cancer. Many studies have confirmed the findings for risk, but few have examined aggressiveness and other clinical variables in detail. Additionally, Gleason score is typically used as a surrogate for the primary end point of prostate cancer mortality. We investigated whether the 8q24 and 17q risk variants are associated...
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