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Article

Role of the Cytosolic Loop C2 and the C Terminus of YidC in Ribosome Binding and Insertion Activity.

The Journal of biological chemistry - 10 Jul 2015

Geng Yanping, Kedrov Alexej, Caumanns Joseph J, Crevenna Alvaro H, Lamb Don C, Beckmann Roland, Driessen Arnold J M

Abstract excerpt

Members of the YidC/Oxa1/Alb3 protein family mediate membrane protein insertion, and this process is initiated by the assembly of YidC·ribosome nascent chain complexes at the inner leaflet of the lipid bilayer. The positively charged C terminus of Escherichia coli YidC plays a significant role in ribosome binding but is not the sole determinant because deletion does not completely abrogate ribosome binding. The...

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Identifiers

PMID: 26023232
DOI: 10.1074/jbc.M115.650309
PMCID: PMC4498064

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Role of the Cytosolic Loop C2 and the C Terminus of YidC in Ribosome Binding and Insertion Activity.PMID 26023232Read ↗

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