Article

Protein Interactomes Identify Distinct Pathways for <i>Streptococcus mutans</i> YidC1 and YidC2 Membrane Protein Insertases

2020-04-09

Abstract excerpt

Virulence properties of cariogenic Streptococcus mutans depend on integral membrane proteins. Bacterial protein trafficking involves the co-translational signal recognition particle (SRP) pathway components Ffh and FtsY, the SecY translocon, and membrane-localized YidC chaperone/insertases. Unlike Escherichia coli, S. mutans survives loss of the SRP pathway. In addition, S. mutans has two yidC paralogs. The Δ...

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Literature Corpus work: aafc087f-fdd7-5d6a-b819-d548c01ba0e1
DOI: 10.1101/2020.04.07.031013

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