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Article

A note on permutation tests for genetic association analysis of quantitative traits when variances are heterogeneous.

Genetic epidemiology - 1 Dec 2009

Posthuma Danielle, de Koning Dirk-Jan, Dolan Conor, Goddard Michael E, Visscher Peter M

Abstract excerpt

The genetic dissection of quantitative traits, or endophenotypes, usually involves genetic linkage or association analysis in pedigrees and subsequent fine mapping association analysis in the population. The ascertainment procedure for quantitative traits often results in unequal variance of observations. For example, some phenotypes may be clinically measured whilst others are from self-reports, or phenotypes...

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PMID: 19365861
DOI: 10.1002/gepi.20423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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