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Article

Significance thresholds for quantitative trait locus mapping under selective genotyping.

Genetics - 1 Nov 2007

Manichaikul Ani, Palmer Abraham A, Sen Saunak, Broman Karl W

Abstract excerpt

In the case of selective genotyping, the usual permutation test to establish statistical significance for quantitative trait locus (QTL) mapping can give inappropriate significance thresholds, especially when the phenotype distribution is skewed. A stratified permutation test should be used, with...

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Identifiers

PMID: 17720902
DOI: 10.1534/genetics.107.080093
PMCID: PMC2147971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17720902-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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