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Meta-analysis of linkage studies for Alzheimer's disease--a web resource.

Neurobiology of aging - 1 Jul 2009

Butler Amy W, Ng Mandy Y M, Hamshere Marian L, Forabosco Paola, Wroe Richard, Al-Chalabi Ammar, Lewis Cathryn M, Powell John F

Abstract excerpt

Familial late-onset Alzheimer's disease (LOAD) shows high heritability. However, with the exception of ApoE, no well-replicated susceptibility genes have been identified to date. Several genome-wide linkage studies have nominated potential susceptibility loci but results are inconsistent, with individual scans showing few significant LOD scores. We have pooled linkage results from five independent genome scans...

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PMID: 19362756
DOI: 10.1016/j.neurobiolaging.2009.03.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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