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Article

Single-nucleotide polymorphism c.474G>A in the SEPT12 gene is a predisposing factor in male infertility.

Molecular reproduction and development - 1 Feb 2020

Rafaee Alemeh, Mohseni Meybodi Anahita, Yaghmaei Parichehreh, Hosseini Seyedeh Hanieh, Sabbaghian Marjan

Abstract excerpt

SEPT12 is a testis-specific gene involved in the terminal differentiation of male germ cells. SEPT12 protein is required for sperm head-tail formation and acts as a fundamental constituent of sperm tail annulus. In this study, we screened genetic variations in exons 5, 6, 7 of the SEPT12 and assessed the annulus status in teratozoospermic, globozoospermic, and patients with immotile short tail sperm. DNA...

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Identifiers

PMID: 31880374
DOI: 10.1002/mrd.23310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Single-nucleotide polymorphism c.474G>A in the SEPT12 gene is a predisposing factor in male infertility.PMID 31880374Read ↗

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