Article
Motor complications in patients form the German Competence Network on Parkinson's disease and the DRD3 Ser9Gly polymorphism.
Movement disorders : official journal of the Movement Disorder Society - 15 May 2009
Paus Sebastian, Gadow Franziska, Knapp Michael, Klein Christine, Klockgether Thomas, Wüllner Ullrich
Abstract excerpt
In addition to levodopa treatment and disease duration, genetic predisposition might contribute to the development of medication-related complications in Parkinson's disease (PD). As recent observations indicate the dopamine D(3) receptor (DRD3) to modulate both therapeutic action of levodopa and dyskinesia, we reappraised the impact of the DRD3 Ser9Gly polymorphism on development of motor complications in a...
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