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Article

Behavioral addictions in early-onset Parkinson disease are associated with DRD3 variants.

Parkinsonism & related disorders - 1 Apr 2018

Castro-Martínez Xochitl Helga, García-Ruiz Pedro J, Martínez-García Carlos, Martínez-Castrillo Juan Carlos, Vela Lydia, Mata Marina, Martínez-Torres Irene, Feliz-Feliz Cici, Palau Francesc, Hoenicka Janet

Abstract excerpt

BACKGROUND: Impulse control disorders (ICDs) comprise abnormal behaviors frequently found in patients with Parkinson's disease (PD) receiving antiparkinsonian medication. ICDs in PD would develop when dopaminergic treatment overstimulates the dopamine receptor D3 (DR3). Here we studied whether DR3 gene (DRD3) is associated to ICD in PD patients with early-onset (EOPD). METHODS: We performed association analysis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29361389
DOI: 10.1016/j.parkreldis.2018.01.010

Genes

DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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