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Pharmacogenetics and levodopa induced motor complications

25 Oct 2018

Abstract excerpt

AIM: L-dopa remains the most effective symptomatic therapy for Parkinson's disease (PD) but unfortunately, its chronic use is often associated with motor complications. This review highlights the importance of pharmacogenetics in an individualised PD therapeutic approach. MATERIAL AND METHODS: review of the literature was done. RESULTS: PD patients show remarkable heterogeneity in their response to L-dopa and...

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PMID: 30359152
DOI: 10.1080/00207454.2018.1538993

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