Article
Mutations of calcium channel beta subunit genes in mice.
Biological chemistry - 1 Jan 2000
Freise D, Himmerkus N, Schroth G, Trost C, Weissgerber P, Freichel M, Flockerzi V
Abstract excerpt
Ca2+ influx through high voltage activated Ca2+ channels initiates a number of physiological processes including e.g. excitation-contraction coupling in cardiac myocytes and excitation-transcription coupling in neurones. The Ca2+ channels involved are complexes of a pore-forming alpha1 subunit, a transmembrane delta subunit disulfide-linked to an extracellular alpha2 subunit, a intracellular beta subunit and, at...
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