Article
Phenotypic analysis of vertigo 2 Jackson mice with a Kcnq1 potassium channel mutation.
Experimental animals - 1 Jul 2007
Takagi Takeshi, Nishio Hajime, Yagi Takeo, Kuwahara Masayoshi, Tsubone Hirokazu, Tanigawa Nobuhiko, Suzuki Koichi
Abstract excerpt
The KCNQ1 gene encodes a voltage-dependent potassium ion channel, and mutations in this gene are the most common cause of congenital long QT syndrome (LQTS). In the present study, we investigated the various phenotypic characteristics of vertigo 2 Jackson (C3H/HeJCrl-Kcnq1(vtg-2J)/J) mice with a...
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