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Article

Molecular Profiling of Clear Cell Ovarian Cancers: Identifying Potential Treatment Targets for Clinical Trials.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2016

Friedlander Michael L, Russell Kenneth, Millis Sherri, Gatalica Zoran, Bender Ryan, Voss Andreas

Abstract excerpt

BACKGROUND: Advanced stage/recurrent clear cell ovarian cancers (CCOCs) are characterized by a low response to chemotherapy and a poor prognosis. There is growing interest in investigating novel/molecular targeted therapies in patients with CCOC in histotype-specific trials. However, CCOCs are not a uniform entity and comprise a number of molecular subtypes and it is unlikely that a single approach to treatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26937756
DOI: 10.1097/IGC.0000000000000677
PMCID: PMC4841290

Genes

KRAS

Provenance

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