Article
A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder.
Archives of general psychiatry - 1 Apr 2009
Wendland Jens R, Moya Pablo R, Timpano Kiara R, Anavitarte Adriana P, Kruse Matthew R, Wheaton Michael G, Ren-Patterson Renee F, Murphy Dennis L
Abstract excerpt
CONTEXT: Recent evidence from linkage analyses and follow-up candidate gene studies supports the involvement of SLC1A1, which encodes the neuronal glutamate transporter, in the development of obsessive-compulsive disorder (OCD). OBJECTIVES: To determine the role of genetic variation of SLC1A1 in OCD in a large case-control study and to better understand how SLC1A1 variation affects functionality. DESIGN: A...
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