Article
Association of the SLC1A1 glutamate transporter gene and obsessive-compulsive disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2007
Stewart S Evelyn, Fagerness Jesen A, Platko Jill, Smoller Jordan W, Scharf Jeremiah M, Illmann Cornelia, Jenike Eric, Chabane Nadia, Leboyer Marion, Delorme Richard, Jenike Michael A, Pauls David L
Abstract excerpt
CONTEXT: Obsessive-Compulsive Disorder (OCD) is a debilitating illness with putative glutamatergic abnormalities. Two separate proximal haplotypes in the glutamate transporter gene, SLC1A1, were recently reported to be associated with OCD among males, but replication is required. OBJECTIVES: This study examines SLC1A1 as a candidate gene for OCD and explores gender influences. It was hypothesized that a...
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