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Article

Association testing of the positional and functional candidate gene SLC1A1/EAAC1 in early-onset obsessive-compulsive disorder.

Archives of general psychiatry - 1 Jul 2006

Dickel Diane E, Veenstra-VanderWeele Jeremy, Cox Nancy J, Wu Xiaolin, Fischer Daniel J, Van Etten-Lee Michelle, Himle Joseph A, Leventhal Bennett L, Cook Edwin H, Hanna Gregory L

Abstract excerpt

CONTEXT: The first 2 independent linkage studies for obsessive-compulsive disorder (OCD) identified a region on 9p24 with suggestive evidence for linkage. The glutamate transporter gene solute carrier family 1, member 1 (SLC1A1) is a promising functional candidate in this region because altered glutamatergic concentrations have been found in the striatum and anterior cingulate in neuroimaging studies of pediatric...

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PMID: 16818867
DOI: 10.1001/archpsyc.63.7.778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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