Article
Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter.
Schizophrenia research - 1 Jun 2009
Treutlein Jens, Mühleisen Thomas W, Frank Josef, Mattheisen Manuel, Herms Stefan, Ludwig Kerstin U, Treutlein Tsendsesmee, Schmael Christine, Strohmaier Jana, Bösshenz Katja Veronika, Breuer René, Paul Torsten, Witt Stephanie H, Schulze Thomas G, Schlösser Ralf G M, Nenadic Igor, Sauer Heinrich, Becker Tim, Maier Wolfgang, Cichon Sven, Nöthen Markus M, Rietschel Marcella
Abstract excerpt
Recent linkage and association data have implicated the Glutamate Receptor Delta 1 (GRID1) locus in the etiology of schizophrenia. In this study, we sought to test whether variants in the promoter region are associated with this disorder. The distribution of CpG islands, which are known to be rel...
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