Article
Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Aug 2004
Chen Xiangning, Dunham Cynthia, Kendler Seth, Wang Xu, O'Neill F Anthony, Walsh Dermot, Kendler Kenneth S
Abstract excerpt
The regulator of the G-protein signaling 4 (RGS4) gene was shown to have a different expression pattern in schizophrenia patients in a microarray study. A family-based study subsequently implicated the association of this gene with schizophrenia. We replicated the study with our sample from the Irish Study of High Density Schizophrenia Families (ISHDSF). Single marker transmission disequilibrium tests (TDT) for...
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