Article
A case-control association study between the GRID1 gene and schizophrenia in the Chinese Northern Han population.
Schizophrenia research - 1 Jul 2007
Guo Sheng-Zhen, Huang Ke, Shi Yong-Yong, Tang Wei, Zhou Jian, Feng Guo-Yin, Zhu Shao-Min, Liu Hui-Jun, Chen Yi, Sun Xiao-Dong, He Lin
Abstract excerpt
The glutamatergic dysfunction hypothesis of schizophrenia implicates the genes involved in glutamatergic transmission as strong candidates for schizophrenia-susceptibility. Recent linkage and association studies have identified the glutamate receptor, ionotropic, delta 1 gene GRID1 on 10q22 as a strong candidate for schizophrenia. In this current association study, we genotyped five genetic variants within the...
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